Alpha granule

 ( Growth Factors ) 

Alpha granules, (α-granules) also known as platelet alpha-granules are a cellular component of platelets. contain different types of granules that perform different functions, and include alpha granules, dense granules, and . Of these, alpha granules are the most common, making up 50% to 80% of the secretory granules. Alpha granules contain several .

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Contents Contents include insulin-like growth factor 1, platelet-derived growth factors, TGF beta, platelet factor 4 (which is a heparin-binding chemokine) and other clotting proteins (such as thrombospondin, fibronectin, factor V, and von Willebrand factor).

The alpha granules express the adhesion molecule P-selectin

and CD63.

(2025). 9780123744197, Academic Press. . ISBN 9780123744197

These are transferred to the membrane after synthesis.

The other type of granules within platelets are called dense granules.

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Clinical significance A deficiency of alpha granules is known as gray platelet syndrome.

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See also

• Platelet rich fibrin

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